Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5647638 | 0.90 | F10 (0.50) | MCHR1HTR2CMAPTTP53PDGFRB | |
| SCHEMBL5644738 | 0.81 | PDGFRB (0.42) | TP53PDGFRBPDGFRAKDM4EALDH1A1 | |
| SCHEMBL5646648 | 0.78 | MCHR1 (0.68) | MCHR1HTR2CMAPTTP53F10 | |
| SCHEMBL5644296 | 0.73 | MCHR1 (0.69) | MCHR1HTR2CMAPTKDM4EALDH1A1 | |
| SCHEMBL14619972 | 0.72 | MCHR1 (0.56) | MCHR1HTR2CMAPTNPC1HDAC1 | |
| SCHEMBL5649106 | 0.72 | MCHR1 (0.68) | MCHR1HTR2CMAPTF10KDM4E | |
| SCHEMBL5651638 | 0.69 | MCHR1 (0.68) | MCHR1HTR2C | |
| SCHEMBL5648264 | 0.68 | PDGFRB (0.48) | PDGFRBPDGFRAACHE | |
| SCHEMBL5644842 | 0.68 | MCHR1 (0.70) | MCHR1HTR2CTP53HDAC1 | |
| SCHEMBL5646136 | 0.66 | IRAK4 (0.47) | TP53PDGFRBPDGFRAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |