Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 13/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 13/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644738 | 0.77 | PDGFRB (0.42) | PDGFRBPDGFRAACHE | |
| SCHEMBL5645610 | 0.74 | MCHR1 (0.45) | PDGFRBPDGFRA | |
| SCHEMBL5646416 | 0.73 | PDGFRB (0.47) | PDGFRBPDGFRA | |
| SCHEMBL17450407 | 0.70 | ALDH1A1 (0.62) | ACHE | |
| SCHEMBL12471340 | 0.69 | PDE10A (0.47) | PDE10A | |
| Hydrochloric Acid SCHEMBL11277758 | 0.66 | ACHE (0.51) | ACHE | |
| SCHEMBL29922921 | 0.65 | NQO2 (0.56) | — | |
| SCHEMBL5696548 | 0.65 | NQO2 (0.56) | — | |
| SCHEMBL3391498 | 0.65 | PDGFRB (0.57) | PDGFRBPDGFRA | |
| SCHEMBL22185958 | 0.64 | PDGFRB (0.50) | PDGFRBPDGFRAEGFRPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20050209213-A1 | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| EP-1447402-A1 | QUINOLINE COMPOUND | Takeda Chemical Industries, Ltd. (JP) | 2004-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209213-A1 | Quinoline compound | MC1R, MC2R, TYR | PDGFRB 2194/4885PDGFRA 2217/4885EGFR 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.