Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557370 | 1.00 | PDE4A (0.57) | PDE4ATSHRCYP2C9LMNAUSP2 | |
| SCHEMBL22806523 | 0.90 | PDE4A (0.50) | PDE4ATSHRCYP2C9LMNAUSP2 | |
| SCHEMBL21617331 | 0.84 | PDE4A (0.57) | PDE4ATSHRCYP2C9LMNAUSP2 | |
| SCHEMBL22806520 | 0.82 | PDE4A (0.55) | PDE4ATSHRCYP2C9LMNAUSP2 | |
| SCHEMBL23581426 | 0.81 | SLC1A3 (0.39) | PDE4ALMNAUSP2SLCO1B1OR51E2 | |
| SCHEMBL28199325 | 0.81 | PDE4A (0.35) | PDE4ALMNAMGAMSIL3MBTL1 | |
| SCHEMBL22688963 | 0.81 | TSHR (0.43) | PDE4ATSHRCYP2C9PGDALDH1A1 | |
| SCHEMBL29455702 | 0.81 | TSHR (0.43) | PDE4ATSHRCYP2C9PGDALDH1A1 | |
| SCHEMBL10146952 | 0.79 | TSHR (0.41) | PDE4ATSHRCYP2C9ALDH1A1 | |
| SCHEMBL19741472 | 0.78 | LMNA (0.50) | PDE4ALMNAUSP2SLCO1B1MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536838-B1 | Hyposensibilisation by hydroxyalkyl starch allergen conjugates | FRESENIUS KABI DE GMBH (DE) | 2007-01-31 | — | — | EP | disclosed |