Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788468 | 0.82 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2PDE10APOLB | |
| SCHEMBL14727986 | 0.81 | TRPM4 (0.33) | TRPM4NQO2 | |
| SCHEMBL17212389 | 0.78 | SMAD3 (0.33) | KDM4ESMN1; SMN2POLBACHEMEN1 | |
| SCHEMBL9326676 | 0.77 | MYC (0.52) | MYCMAXKDM4ELMNASMN1; SMN2 | |
| SCHEMBL20352441 | 0.73 | RAB9A (0.45) | KDM4ELMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1256551 | 0.72 | ACHE (0.61) | KDM4ELMNASMN1; SMN2PDE10APOLB | |
| SCHEMBL14727987 | 0.72 | CYP2A6 (0.35) | CYP1A2HPGD | |
| SCHEMBL14727985 | 0.72 | — | — | |
| SCHEMBL20696076 | 0.71 | ACHE (0.59) | KDM4ELMNASMN1; SMN2PDE10APOLB | |
| Methane SCHEMBL10433561 | 0.71 | ACHE (0.59) | KDM4ELMNASMN1; SMN2PDE10APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001406-A2 | ARYL-CONTAINING MACROCYCLIC COMPOUNDS | CHIRON CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |