Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 5/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14623153 | 1.00 | CAPN1 (0.44) | CAPN1CTSKDPP4DPP9DPP7 | |
| SCHEMBL2739549 | 1.00 | CAPN1 (0.44) | CAPN1CTSKDPP4DPP9DPP7 | |
| SCHEMBL8817388 | 0.89 | CAPN1 (0.46) | CAPN1CTSKCTSBSLC7A5 | |
| SCHEMBL16565969 | 0.89 | CAPN1 (0.46) | CAPN1CTSKCTSBSLC7A5 | |
| SCHEMBL3487246 | 0.89 | CAPN1 (0.46) | CAPN1CTSKCTSBSLC7A5 | |
| SCHEMBL2475740 | 0.89 | CAPN1 (0.46) | CAPN1CTSKCTSBSLC7A5 | |
| SCHEMBL9572309 | 0.89 | CAPN1 (0.46) | CAPN1CTSKCTSBSLC7A5 | |
| SCHEMBL20375816 | 0.84 | PAX8 (0.47) | CAPN1CTSKDPP4DPP7CTSB | |
| SCHEMBL20609254 | 0.84 | PAX8 (0.47) | CAPN1CTSKDPP4DPP7CTSB | |
| SCHEMBL8621285 | 0.84 | PAX8 (0.47) | CAPN1CTSKDPP4DPP7CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006103274-A9 | AGE INHIBITORS | PHARMAMENS (FR) | 2007-01-18 | — | — | WO | disclosed |