SCHEMBL2475740

SCHEMBL2475740

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nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 7/20 0.46
SLC7A5 Q01650 1/20 0.45
CTSB P07858 5/20 0.40
LARS1 Q9P2J5 1/20 0.40
SCN9A Q15858 3/20 0.39
CTSK P43235 1/20 0.39
ANPEP P15144 2/20 0.39
RNPEP Q9H4A4 2/20 0.39
DNPEP Q9ULA0 1/20 0.39
AAK1 Q2M2I8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817388 1.00 CAPN1 (0.46) CAPN1SLC7A5CTSBLARS1SCN9A
SCHEMBL9572309 1.00 CAPN1 (0.46) CAPN1SLC7A5CTSBLARS1SCN9A
SCHEMBL3487246 1.00 CAPN1 (0.46) CAPN1SLC7A5CTSBLARS1SCN9A
SCHEMBL16565969 1.00 CAPN1 (0.46) CAPN1SLC7A5CTSBLARS1SCN9A
SCHEMBL16897943 0.92 CAPN1 (0.41) CAPN1SLC7A5CTSBLARS1
SCHEMBL4232298 0.92 CAPN1 (0.41) CAPN1SLC7A5CTSBLARS1
SCHEMBL13039705 0.92 CAPN1 (0.41) CAPN1SLC7A5CTSBLARS1
SCHEMBL17347917 0.90 CAPN1 (0.48) CAPN1SLC7A5CTSBLARS1
SCHEMBL14899283 0.90 CAPN1 (0.45) CAPN1SLC7A5CTSBLARS1SCN9A
SCHEMBL2739549 0.89 CAPN1 (0.44) CAPN1SLC7A5CTSBCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024229370-A1 COMPOSITIONS AND METHODS FOR TREATING GVHD CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024229350-A1 IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS FOR DIABETES CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024229380-A1 IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS IN AUTOIMMUNE LIVER DISEASES CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
WO-2024229432-A1 SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE CARTESIAN THERAPEUTICS, INC. (US) 2024-11-07 WO disclosed
EP-4429662-A1 MULTIPLE DOSING WITH VIRAL VECTORS Cartesian Therapeutics, Inc. (US) 2024-09-18 EP disclosed
EP-4415760-A1 VIRAL VECTOR DOSING PROTOCOLS Cartesian Therapeutics, Inc. (US) 2024-08-21 EP disclosed
EP-4319747-A1 SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT IN COMBINATION WITH HIGH AFFINITY IL-2 RECEPTOR AGONISTS TO ENHANCE IMMUNE TOLERANCE Selecta Biosciences, Inc. (US) 2024-02-14 EP disclosed
CN-115011418-B Liquid composition with stabilized protease activity 南京百斯杰生物工程有限公司 2024-02-06 CN disclosed
EP-4274571-A1 VIRAL VECTOR DOSING PROTOCOLS Selecta Biosciences, Inc. (US) 2023-11-15 EP disclosed
WO-2023196566-A1 HIGH AFFINITY IL-2 RECEPTOR AGONISTS AND IMMUNOSUPPRESSANTS TO ENHANCE IMMUNE TOLERANCE SELECTA BIOSCIENCES, INC. (US) 2023-10-12 WO disclosed
EP-3976802-A1 METHODS AND COMPOSITIONS FOR ATTENUATED ANTI-VIRAL TRANSFER VECTOR IMMUNE RESPONSE Selecta Biosciences, Inc. (US) 2022-04-06 EP disclosed
EP-3962537-A1 METHODS FOR TREATMENT OF SUBJECTS WITH PREEXISTING IMMUNITY TO VIRAL TRANSFER VECTORS Selecta Biosciences, Inc. (US) 2022-03-09 EP disclosed
WO-2022022599-A1 METHOD FOR AMPLIFYING IN-VITRO INDUCED CD4 +FOXP3 +CD69 +TREG AND USE THEREOF 浙江大学 2022-02-03 WO disclosed
US-11041207-B2 Method for predicting a subject's response to valproic acid therapy THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2021-06-22 US disclosed
US-20140349969-A1 COMPOUNDS AND METHODS FOR TREATING PAIN AKRON MOLECULES AG (AT) 2014-11-27 US disclosed
US-20130252924-A1 Compounds and Methods for Treating Pain AKRON MOLECULES GMBH (AT) 2013-09-26 US disclosed
EP-2373797-A1 SCREENING METHOD FOR IDENTIFYING GENES INVOLVED IN PLANT CELL CYCLE VIB VZW (BE) 2011-10-12 EP disclosed
WO-2010066849-A1 SCREENING METHOD FOR IDENTIFYING GENES INVOLVED IN PLANT CELL CYCLE VIB VZW (BE) 2010-06-17 WO disclosed
US-20100068147-A1 DENGUE DIAGNOSIS AND TREATMENT Agency for Science , Technology and Research (SG) 2010-03-18 US disclosed
WO-1997032605-A1 CYTOMEGALOVIRUS NUCLEIC ACIDS ENCODING PROTEINS HAVING NORMAL OR ALTERED CLASS I MHC BINDING AND TREATMENT OF DISEASES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1997-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140349969-A1 COMPOUNDS AND METHODS FOR TREATING PAIN TRPV1, ACHE, OPRL1 CAPN1 1340/4885SLC7A5 4209/4885CTSB 345/4885
US-20130252924-A1 Compounds and Methods for Treating Pain TRPV1, ACHE, OPRL1 CAPN1 1340/4885SLC7A5 4209/4885CTSB 345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.