Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1881308 | 0.85 | MTNR1A (0.40) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL14624164 | 0.82 | HTR1B (0.47) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL14624578 | 0.81 | HTR1B (0.56) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL1880746 | 0.79 | HTR1B (0.43) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL7415604 | 0.78 | MTNR1A (0.42) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL1875313 | 0.77 | HTR1A (0.54) | HTR1BHTR1AHTR1DDRD2DRD4 | |
| SCHEMBL1879389 | 0.77 | MTNR1A (0.41) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL7415569 | 0.77 | CGAS (0.45) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL14624157 | 0.75 | HTR1B (0.48) | HTR1BHTR1AHTR1DMTNR1AMTNR1B | |
| SCHEMBL13478774 | 0.73 | MTNR1A (0.44) | HTR1BHTR1AHTR1DMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |