SCHEMBL14623643

SCHEMBL14623643

CON(C)C(=O)NC1CCc2c(c3cc(N)ccc3n2Cc2cccc(F)c2)C1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 19/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13478792 0.92 PTGDR2 (0.48) PTGDR2
SCHEMBL13478767 0.89 PTGDR2 (0.47) PTGDR2
SCHEMBL1883635 0.89 PTGDR2 (0.45) PTGDR2
SCHEMBL14625198 0.86 PTGDR2 (0.47) PTGDR2
SCHEMBL14624682 0.85 PTGDR2 (0.45) PTGDR2
SCHEMBL14624694 0.85 PTGDR2 (0.47) PTGDR2
SCHEMBL14623711 0.83 PTGDR2 (0.48) PTGDR2
SCHEMBL1878612 0.82 PTGDR2 (0.48) PTGDR2
SCHEMBL14624592 0.82 PTGDR2 (0.42) PTGDR2
SCHEMBL1877119 0.81 PTGDR2 (0.47) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007002181-A2 TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) ELI LILLY AND COMPANY (US) 2007-01-04 WO disclosed