Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13478767 | 0.93 | PTGDR2 (0.47) | PTGDR2KMT2AHDAC1HDAC6SIGMAR1 | |
| SCHEMBL1877864 | 0.90 | PTGDR2 (0.45) | PTGDR2KMT2AL3MBTL1HDAC1HDAC6 | |
| SCHEMBL1878920 | 0.89 | PTGDR2 (0.44) | PTGDR2KMT2AL3MBTL1HDAC1HDAC6 | |
| SCHEMBL14623711 | 0.88 | PTGDR2 (0.48) | PTGDR2KMT2ASIGMAR1TBXA2RPTGDR | |
| SCHEMBL14625198 | 0.87 | PTGDR2 (0.47) | PTGDR2KMT2AHDAC1HDAC6SIGMAR1 | |
| SCHEMBL13478792 | 0.87 | PTGDR2 (0.48) | PTGDR2HDAC1HDAC6 | |
| SCHEMBL14624694 | 0.86 | PTGDR2 (0.47) | PTGDR2KMT2AHDAC1HDAC6SIGMAR1 | |
| SCHEMBL14623643 | 0.85 | PTGDR2 (0.46) | PTGDR2 | |
| SCHEMBL14624589 | 0.83 | PTGDR2 (0.41) | PTGDR2KMT2ASIGMAR1TBXA2RPTGDR | |
| SCHEMBL14624299 | 0.82 | PTGDR2 (0.42) | PTGDR2HDAC1HDAC6TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |