Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | JUN | P05412 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462390 | 1.00 | ALDH1A1 (0.65) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL11938178 | 0.95 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1GAA | |
| SCHEMBL2457630 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL2457625 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL10464264 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL10465344 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4EGAASMN1; SMN2 | |
| SCHEMBL11289654 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL2457107 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL10747248 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KDM4E | |
| SCHEMBL2457110 | 0.84 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473199-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | Brain Watch Ltd. (IL) | 2012-07-11 | — | — | EP | disclosed |
| US-20120156139-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEROF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2012-06-21 | — | — | US | disclosed |
| WO-2011024156-A1 | ISOTOPICALLY LABELED NEUROCHEMICAL AGENTS AND USES THEREOF FOR DIAGNOSING CONDITIONS AND DISORDERS | BRAIN WATCH LTD. (IL) | 2011-03-03 | — | — | WO | disclosed |