Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | JUN | P05412 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | VCP | P55072 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747248 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL2457107 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL30958855 | 1.00 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL11289654 | 0.95 | ALDH1A1 (0.65) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL2457625 | 0.93 | ALDH1A1 (0.62) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL2457630 | 0.93 | ALDH1A1 (0.62) | ALDH1A1MAPTJUNNFKB1KMT2A | |
| SCHEMBL6449146 | 0.92 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ARAB9AGAA | |
| SCHEMBL10466948 | 0.92 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ARAB9AGAA | |
| SCHEMBL6449141 | 0.92 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2ARAB9AGAA | |
| SCHEMBL11938178 | 0.90 | ALDH1A1 (0.72) | ALDH1A1MAPTJUNNFKB1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4005127-A | L-Dopa process and intermediates | MONSANTO COMPANY (US) | 1977-01-25 | — | — | US | claimed |
| EP-2514739-B1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | UNIV NORTHWEST (CN) | 2016-12-21 | — | — | EP | disclosed |
| EP-2514739-A1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | Northwest University (CN) | 2012-10-24 | — | — | EP | disclosed |
| US-8017786-B2 | Substituted β-phenyl-α-hydroxy-propanoic acid, synthesis method and use thereof | NORTHWEST UNIVERSITY (CN) | 2011-09-13 | — | — | US | disclosed |
| US-20090131677-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY-PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | NORTHWEST UNIVERSITY (CN) | 2009-05-21 | — | — | US | disclosed |
| EP-2019090-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | Northwest University (CN) | 2009-01-28 | — | — | EP | disclosed |
| EP-0257920-B1 | PROCESS FOR L-DOPA | MERCK & CO. INC. (US) | 1990-10-31 | — | — | EP | disclosed |
| EP-0257920-A1 | Process for L-dopa | MERCK & CO. INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4716246-A | Process for L-dopa | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |
| EP-0104375-B1 | PHOSPHORUS-CONTAINING BIPHENYL DERIVATIVES AND THEIR USE IN ASYMMETRIC HYDROGENATION AND ENATIOSELECTIVE HYDROGEN SHIFTS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-10-15 | — | — | EP | disclosed |
| US-4294989-A | OPTICALLY ACTIVE HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4265827-A | METHYLCYCOHEXYL-O-ANISYLARSINE OPTICALLY ACTIVE CATALYST | MONSANTO COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
| US-4261919-A | OF BETA-SUBSTITUTED-ALPHA-ACYLAMIDO-ACRYLIC ACIDS TO YIELD OPTICALLY ACTIVE MIXTURE | MONSANTO COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4220590-A | OPTICALLY ACTIVE BIS PHOSPHINE COMPOUNDS | MONSANTO COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4142992-A | ASYMMETRIC CATALYSIS | MONSANTO COMPANY (US) | 1979-03-06 | — | — | US | disclosed |
| US-4124533-A | HYDROGENATION CATALYSTS | MONSANTO COMPANY (US) | 1978-11-07 | — | — | US | disclosed |
| US-4038414-A | ANTIARRHYTHMIA AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-07-26 | — | — | US | disclosed |
| US-4014920-A | N-cinnamylcarbamic acid esters | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-4008281-A | BIS-PHOSPHINE | MONSANTO COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-4005127-A | L-Dopa process and intermediates | MONSANTO COMPANY (US) | 1977-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131677-A1 | SUBSTITUTED BETA-PHENYL-ALPHA-HYDROXY-PROPANOIC ACID, SYNTHESIS METHOD AND USE THEREOF | P4HA1, HAO1, PCCA | ALDH1A1 353/4885MAPT 3739/4885JUN 1825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.