Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876121 | 0.90 | PTGDR2 (0.41) | PTGDR2ALDH1A1L3MBTL1SIGMAR1MTNR1A | |
| SCHEMBL1880816 | 0.89 | PTGDR2 (0.41) | PTGDR2ALDH1A1L3MBTL1SIGMAR1MTNR1A | |
| SCHEMBL13478778 | 0.88 | PTGDR2 (0.45) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL14623578 | 0.88 | PTGDR2 (0.45) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL13478793 | 0.87 | PTGDR2 (0.44) | PTGDR2SIGMAR1MTNR1AMTNR1BTBXA2R | |
| SCHEMBL13478781 | 0.85 | MTNR1A (0.51) | PTGDR2SIGMAR1MTNR1AMTNR1BTBXA2R | |
| SCHEMBL14625188 | 0.85 | PTGDR2 (0.44) | PTGDR2SIGMAR1MTNR1AMTNR1BTBXA2R | |
| SCHEMBL14623571 | 0.85 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL14625190 | 0.84 | PTGDR2 (0.42) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR | |
| SCHEMBL14624573 | 0.83 | PTGDR2 (0.41) | PTGDR2MTNR1AMTNR1BTBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |