Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | CCKAR | P32238 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878655 | 0.89 | PTGDR2 (0.40) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14625190 | 0.89 | PTGDR2 (0.42) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14623578 | 0.87 | PTGDR2 (0.45) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL13478778 | 0.87 | PTGDR2 (0.45) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL13478793 | 0.87 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14625188 | 0.84 | PTGDR2 (0.44) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL13478781 | 0.84 | MTNR1A (0.51) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14623571 | 0.84 | PTGDR2 (0.42) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14624166 | 0.83 | PTGDR2 (0.41) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B | |
| SCHEMBL14625187 | 0.82 | PTGDR2 (0.43) | PTGDR2TBXA2RPTGDRMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002181-A2 | TETRAHYDROCARBAZOLE DERIVATIVES USEFUL AS ANDROGEN RECEPTOR MODULATORS (SARM) | ELI LILLY AND COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |