Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8271684 | 0.79 | NCF1 (0.49) | NCF1NR1H2NR1H3PARP1RXRA | |
| SCHEMBL348618 | 0.79 | HTR1A (0.57) | MCHR1CNR1CNR2MEN1HTT | |
| SCHEMBL13045005 | 0.79 | NCF1 (0.44) | NCF1NR1H2NR1H3PARP1HTT | |
| SCHEMBL17018214 | 0.79 | MCHR1 (0.44) | MCHR1CNR1CNR2CYP2C9MEN1 | |
| SCHEMBL15923479 | 0.78 | HTR1A (0.53) | HTTKCNH2DYRK3PRKD3MAP4K4 | |
| SCHEMBL11011220 | 0.78 | NCF1 (0.48) | NCF1NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL10203093 | 0.77 | NR1H2 (0.43) | NCF1NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL1091092 | 0.77 | KDM4E (0.49) | NCF1NR1H2NR1H3PARP1DYRK3 | |
| SCHEMBL16234628 | 0.77 | GSK3A (0.45) | NCF1NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL13409380 | 0.75 | NCF1 (0.46) | NCF1NR1H2NR1H3PARP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4648894-B2 | — | — | 2011-03-09 | — | — | JP | claimed |
| JP-2006519221-A | — | — | 2006-08-24 | — | — | JP | claimed |
| EP-1597253-A2 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES, RETINOPATHIES AND ARTHRITIS | Exonhit Therapeutics S.A. (FR) | 2005-11-23 | — | — | EP | claimed |
| WO-2004076445-A2 | COMPOUNDS AND METHODS OF TREATING CELL PROLIFERATIVE DISEASES, RETINOPATHIES AND ARTHRITIS | EXONHIT THERAPEUTICS SA (FR) | 2004-09-10 | — | — | WO | claimed |