Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003528 | 0.89 | MEN1 (0.61) | NPSR1ACKR3 | |
| SCHEMBL14624960 | 0.88 | ACKR3 (0.51) | ACKR3ALDH1A1SIGMAR1 | |
| SCHEMBL13003526 | 0.78 | ALDH1A1 (0.53) | ACKR3ALDH1A1 | |
| SCHEMBL12310176 | 0.78 | ALDH1A1 (0.76) | NPSR1ALDH1A1 | |
| SCHEMBL13003432 | 0.78 | DRD4 (0.72) | SIGMAR1 | |
| SCHEMBL14624962 | 0.77 | CYP2D6 (0.47) | ACKR3 | |
| SCHEMBL13003552 | 0.77 | KDM4E (0.55) | ALDH1A1 | |
| SCHEMBL14413270 | 0.76 | ALDH1A1 (0.64) | NPSR1ALDH1A1 | |
| SCHEMBL1554194 | 0.76 | TDP1 (0.61) | SIGMAR1 | |
| SCHEMBL13061271 | 0.76 | ALDH1A1 (0.60) | NPSR1ACKR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001975-A1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |