Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003526 | 0.91 | ALDH1A1 (0.53) | ACKR3LMNAALDH1A1 | |
| SCHEMBL14624959 | 0.88 | NPSR1 (0.58) | ACKR3ALDH1A1SIGMAR1 | |
| SCHEMBL23839974 | 0.80 | CAPN1 (0.63) | ACKR3SIGMAR1CAPN1CCR3 | |
| SCHEMBL13003528 | 0.78 | MEN1 (0.61) | ACKR3 | |
| SCHEMBL8228052 | 0.77 | MEN1 (0.57) | ALDH1A1 | |
| SCHEMBL14456741 | 0.77 | MEN1 (0.57) | ALDH1A1 | |
| SCHEMBL14624962 | 0.73 | CYP2D6 (0.47) | ACKR3 | |
| SCHEMBL13003552 | 0.72 | KDM4E (0.55) | ALDH1A1 | |
| SCHEMBL8083501 | 0.72 | ERCC1 (0.65) | ALDH1A1ERCC1ERCC4 | |
| SCHEMBL26082620 | 0.71 | LMNA (0.47) | ACKR3LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001975-A1 | PIPERIDINE DERIVATIVES USEFUL AS HISTAMINE H3 ANTAGONISTS | SCHERING CORPORATION (US) | 2007-01-04 | — | — | WO | disclosed |