Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3245362 | 0.86 | PARP1 (0.50) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL3250282 | 0.86 | ADAM17 (0.46) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL3241767 | 0.86 | ALDH1A1 (0.51) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL3249528 | 0.85 | SMN1; SMN2 (0.43) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL3245630 | 0.85 | EGFR (0.45) | RAB9APOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL3248405 | 0.84 | KDM4E (0.54) | POLBUSP2KDM4EALDH1A1MEN1 | |
| SCHEMBL4153802 | 0.84 | PPARG (0.47) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL14624983 | 0.84 | ALDH1A1 (0.41) | RAB9APOLBUSP2KDM4EALDH1A1 | |
| SCHEMBL3252625 | 0.83 | KDM4E (0.58) | RAB9APOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL3241785 | 0.83 | MEN1 (0.63) | RAB9APOLBMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007003611-A1 | PYRROLOQUINOLINE DERIVATIVES AND THEIR USE AS PROTEIN KINASE INHIBITORS | PIERRE FABRE MEDICAMENT (FR) | 2007-01-11 | — | — | WO | disclosed |