Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4107830 | 0.90 | KMT2A (0.60) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4101718 | 0.90 | MEN1 (0.52) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14625102 | 0.88 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4100116 | 0.88 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4103824 | 0.88 | MEN1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13964537 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14625098 | 0.85 | KMT2A (0.40) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4097043 | 0.83 | KMT2A (0.50) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL4106762 | 0.82 | GPR132 (0.45) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13965247 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001225-A1 | THIOPHENE-2-CARBOXAMIDE DERIVATIVES AS ALPHA 7 NICOTINIC RECEPTOR MODULATORS. | ASTRAZENECA (SE) | 2007-01-04 | — | — | WO | disclosed |