Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12529776 | 0.84 | USP2 (0.48) | MMP13HDAC4HDAC6USP2HSD17B2 | |
| SCHEMBL12529304 | 0.82 | HDAC4 (0.48) | MMP13HDAC4HDAC6USP2HSD17B2 | |
| SCHEMBL14625553 | 0.77 | NPC1 (0.46) | HDAC4HDAC6KMT2AALDH1A1NPC1 | |
| SCHEMBL13211819 | 0.76 | MMP13 (0.84) | MMP13HDAC6NAMPTGRM1KMT2A | |
| SCHEMBL12164140 | 0.75 | DAO (0.55) | HDAC4HDAC6USP2HSD17B2HSD17B1 | |
| SCHEMBL31660043 | 0.74 | MMP13 (0.60) | MMP13ROCK2NAMPTKMT2AMEN1 | |
| SCHEMBL18773998 | 0.74 | MEN1 (0.61) | MMP13HSD17B2HSD17B1ROCK2NAMPT | |
| SCHEMBL12313829 | 0.73 | RAB9A (0.47) | MMP13HDAC4HDAC6USP2HSD17B2 | |
| SCHEMBL10274823 | 0.72 | DAO (0.61) | HDAC4HDAC6HSD17B2HSD17B1DAO | |
| SCHEMBL19210473 | 0.72 | MMP13 (0.53) | MMP13USP2ROCK2ROCK1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010954-A1 | THIOPHENE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-01-25 | — | — | WO | disclosed |