Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4354333 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL3084614 | 0.81 | KDM4E (0.54) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL6073484 | 0.81 | RAB9A (0.49) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL5209725 | 0.81 | PIM1 (0.45) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL14590426 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL7563419 | 0.77 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4ERAB9ANPC1ALDH1A1 | |
| SCHEMBL11249332 | 0.75 | KDM4E (0.37) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL14620831 | 0.75 | SMN1; SMN2 (0.37) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL4439972 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A | |
| SCHEMBL22493927 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |