Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | POLG | P54098 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432220 | 0.88 | POLG (0.61) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL15343924 | 0.88 | POLG (0.61) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL18179803 | 0.88 | POLG (0.61) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL19928646 | 0.86 | POLG (0.54) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL19101684 | 0.84 | POLB (0.69) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL16574639 | 0.81 | POLB (0.59) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL14160634 | 0.81 | PDE3A (0.50) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL429646 | 0.81 | PDE3A (0.50) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL887511 | 0.81 | PDE3A (0.50) | POLBPOLGP2RY2P2RY4P2RY6 | |
| SCHEMBL429647 | 0.81 | PDE3A (0.50) | POLBPOLGP2RY2P2RY4P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007002204-A2 | PYROSEQUENCING METHODS AND RELATED COMPOSTIONS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2007-01-04 | — | — | WO | disclosed |