Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.62 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MERTK | Q12866 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241357 | 0.85 | GRM5 (0.77) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL25053100 | 0.84 | GRM5 (0.63) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL8062288 | 0.83 | EPHX2 (0.74) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL8212053 | 0.83 | PRKAA2 (0.51) | GRM5SMYD3KMT2AMEN1USP30 | |
| SCHEMBL14067296 | 0.82 | GRM5 (0.60) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL2246381 | 0.82 | GRM5 (0.82) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL16394406 | 0.82 | GRM5 (0.88) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL5315579 | 0.81 | SMYD3 (0.60) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL5316723 | 0.81 | GRM5 (0.59) | GRM5SMYD3KMT2AGAAKDM4E | |
| SCHEMBL22449377 | 0.81 | GRM5 (0.80) | GRM5SMYD3KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |