Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626021 | 0.90 | NAMPT (0.42) | MAPTKDM4EKMT2AALDH1A1NAMPT | |
| SCHEMBL14626054 | 0.84 | APEX1 (0.44) | MAPTKDM4ENR1I3ALDH1A1L3MBTL1 | |
| SCHEMBL14625894 | 0.82 | L3MBTL1 (0.54) | MAPTKDM4ESLC6A2SLC6A4KMT2A | |
| SCHEMBL14590662 | 0.81 | NOTUM (0.52) | MAPTKDM4EKMT2ASMN1; SMN2POLB | |
| SCHEMBL14626443 | 0.80 | KMT2A (0.46) | MAPTKDM4ENR1I3KMT2AALDH1A1 | |
| SCHEMBL14625858 | 0.76 | NAMPT (0.54) | MAPTKDM4EKMT2AALDH1A1NAMPT | |
| SCHEMBL14067253 | 0.74 | MAPT (0.44) | MAPTKDM4EKMT2AALDH1A1NAMPT | |
| SCHEMBL14590670 | 0.74 | TP53 (0.60) | MAPTKMT2ASMN1; SMN2MEN1LMNA | |
| SCHEMBL14626226 | 0.73 | APEX1 (0.44) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14626247 | 0.72 | GAA (0.46) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |