Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590670 | 0.82 | TP53 (0.60) | MAPTMEN1KMT2ALMNAHPGD | |
| SCHEMBL14626021 | 0.81 | NAMPT (0.42) | MAPTALDH1A1MEN1KMT2ANPY5R | |
| SCHEMBL6109559 | 0.77 | NPC1 (0.45) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14590662 | 0.75 | NOTUM (0.52) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL14626017 | 0.74 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL14067059 | 0.74 | HPGD (0.47) | MEN1KMT2AALOX5EPHX2KCNT1 | |
| SCHEMBL2632813 | 0.72 | ALDH1A1 (0.52) | MAPTALDH1A1MEN1KMT2AALOX5 | |
| SCHEMBL14067273 | 0.72 | ALDH1A1 (0.54) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4716271 | 0.70 | ITGB3 (0.56) | MAPTALDH1A1MEN1KMT2ANPY5R | |
| SCHEMBL14067235 | 0.70 | NAMPT (0.61) | MAPTALDH1A1MEN1KMT2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325910-B1 | ALIPHATIC NITROGENOUS FIVE-MEMBERED RING COMPOUNDS | MITSUBISHI TANABE PHARMA CORP (JP) | 2008-09-17 | — | — | EP | disclosed |