Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10322693 | 0.90 | PTPN11 (0.56) | MAPTPOLBMEN1KMT2APTPN11 | |
| SCHEMBL31254423 | 0.89 | PTPN11 (0.58) | MAPTPOLBMEN1KMT2APTPN11 | |
| SCHEMBL244184 | 0.89 | KDM4E (0.66) | MAPTKMT2APTPN11SMN1; SMN2ALDH1A1 | |
| SCHEMBL29046853 | 0.87 | PTPN11 (0.60) | MAPTPTPN11SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL30503022 | 0.87 | PTPN11 (0.60) | MAPTPTPN11SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL28059200 | 0.85 | POLB (0.68) | MAPTPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14626215 | 0.85 | MAPT (0.57) | MAPTPOLBMEN1KMT2APTPN11 | |
| SCHEMBL31254484 | 0.85 | PTPN11 (0.55) | MAPTPOLBMEN1KMT2APTPN11 | |
| SCHEMBL31254412 | 0.85 | LMNA (0.56) | MAPTPOLBPTPN11SMN1; SMN2ALDH1A1 | |
| SCHEMBL9299149 | 0.84 | PTPN11 (0.60) | MAPTPOLBPTPN11SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160877-B2 | Aliphatic nitrogen-containing 5-membered ring compound | TANABE SEIYAKU CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |