Niacinamide

Niacinamide

SCHEMBL1462628

NC(=O)c1cccnc1.O=C(O)c1cccnc1

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F7 P08709 1/20 0.85
F3 P13726 1/20 0.85
SARM1 Q6SZW1 1/20 0.85
SIRT2 Q8IXJ6 1/20 0.85
SIRT6 Q8N6T7 1/20 0.85
SIRT1 Q96EB6 1/20 0.85
SIRT3 Q9NTG7 1/20 0.85
SIRT5 Q9NXA8 1/20 0.85
SIRT4 Q9Y6E7 1/20 0.85
ALDH1A1 P00352 2/20 0.81
APP P05067 1/20 0.81
GAA P10253 1/20 0.81
HCAR3 P49019 1/20 0.81
HCAR2 Q8TDS4 1/20 0.81
MKNK1 Q9BUB5 4/20 0.56
MKNK2 Q9HBH9 4/20 0.56
KMO O15229 1/20 0.54
PLOD2 O00469 1/20 0.53
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Niacinamide SCHEMBL28589259 0.94 F7 (0.81) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL29596610 0.94 F7 (0.81) F7F3SARM1SIRT2SIRT6
Niacin SCHEMBL1640446 0.94 ALDH1A1 (0.91) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL675207 0.94 F7 (0.96) F7F3SARM1SIRT2SIRT6
Terephthalamic Acid SCHEMBL7674497 0.93 F7 (0.79) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL460466 0.92 F7 (1.00) F7F3SARM1SIRT2SIRT6
Niacinamide SCHEMBL29624874 0.92
Niacinamide SCHEMBL19978192 0.92
Niacinamide SCHEMBL2926 0.92
Niacinamide SCHEMBL18938563 0.91 F7 (0.76) F7F3SARM1SIRT2SIRT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112114060-A Method for detecting vitamins in formula food with special medical application 特康药业集团有限公司 2020-12-22 CN claimed
US-7666451-B2 Method of treating dyshidrosis(pompholyx) and related dry skin disorders MAZZIO ELIZABETH ANNE 2010-02-23 US claimed
US-7357950-B2 Topical treatment for dyshidrosis (pompholyx) and dry skin disorders MAZZIO ELIZABETH ANNE 2008-04-15 US claimed
US-11852970-B2 Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-26 US disclosed
US-11480877-B2 Resist composition, method for forming resist pattern, and polyphenol compound used therein MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-10-25 US disclosed
CN-114555619-A Compounds and compositions for differential modulation of nicotinamide adenine dinucleotide 麦德龙国际生物科技有限责任公司 2022-05-27 CN disclosed
CN-114235986-A High performance liquid chromatography detection method for contents of vitamins B1, B2, B6, nicotinic acid and nicotinamide 浙江艾兰得生物科技有限公司 2022-03-25 CN disclosed
US-11256170-B2 Compound, resist composition, and method for forming resist pattern using it MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2022-02-22 US disclosed
CN-111272912-B Method for measuring nicotinic acid and nicotinamide in infant rice flour by solid-phase extraction-high performance liquid chromatography 山东省食品药品检验研究院 2022-02-01 CN disclosed
US-20210121469-A1 Edible Energy Composition INTERNATIONAL IP HOLDINGS LLC (US) 2021-04-29 US disclosed
US-20210077517-A1 Edible Energy Composition International IP Holdings (US) 2021-03-18 US disclosed
EP-1706131-A2 HELICAL SYNTHETIC PEPTIDES THAT STIMULATE CELLULAR CHOLESTEROL EFFLUX The Regents of the University of California (US) 2006-10-04 EP disclosed
WO-2005058938-A2 HELICAL SYNTHETIC PEPTIDES THAT STIMULATE CELLULAR CHOLESTEROL EFFLUX THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-06-30 WO disclosed
EP-1469746-A2 MODULAR SYSTEM OF DIETARY SUPPLEMENT COMPOSITIONS COMPRISING VITAMINS Meijer, Jaap (NL) 2004-10-27 EP disclosed
CN-1447680-A Local release system of micronutrients and application thereof NIADYNE CORP (US) 2003-10-08 CN disclosed
WO-2002076436-A2 MODULAR SYSTEM OF DIETARY SUPPLEMENT COMPOSITIONS COMPRISING VITAMINS MEIJER JAAP (NL) 2002-10-03 WO disclosed
EP-0938605-A1 ENZYMATIC METHOD FOR OVERDYEING CELLULOSIC TEXTILES Novo Nordisk Biochem North America, Inc. (US) 1999-09-01 EP disclosed
WO-1998005816-A1 ENZYMATIC METHOD FOR OVERDYEING CELLULOSIC TEXTILES NOVO NORDISK BIOCHEM NORTH AMERICA, INC. (US) 1998-02-12 WO disclosed
EP-0662818-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1995-07-19 EP disclosed
WO-1994007462-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1994-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11480877-B2 Resist composition, method for forming resist pattern, and polyphenol compound used therein SLC11A2, ABCC1, FBL F7 2558/4885F3 3261/4885SARM1 4289/4885
US-11852970-B2 Material for lithography, production method therefor, composition for lithography, pattern formation method, compound, resin, and method for purifying the compound or the resin SLC39A11, CROCC, TERB1 F7 276/4885F3 1179/4885SARM1 3538/4885
US-11256170-B2 Compound, resist composition, and method for forming resist pattern using it RDX, SLC11A2, FBL F7 1629/4885F3 2060/4885SARM1 2822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.