Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3345206 | 0.87 | NAMPT (0.44) | MAPTALDH1A1HRH3KMT2AL3MBTL1 | |
| SCHEMBL30206646 | 0.86 | MAPT (0.58) | MAPTALDH1A1HRH3KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10806945 | 0.85 | MAPT (0.57) | MAPTALDH1A1HRH3KMT2AL3MBTL1 | |
| SCHEMBL7474533 | 0.83 | L3MBTL1 (0.56) | MAPTALDH1A1HRH3KMT2AL3MBTL1 | |
| SCHEMBL14645821 | 0.81 | NPC1 (0.40) | MAPTALDH1A1KMT2AGRM5L3MBTL1 | |
| SCHEMBL20819833 | 0.81 | NPC1 (0.40) | MAPTALDH1A1KMT2AGRM5L3MBTL1 | |
| SCHEMBL9921213 | 0.81 | CHRM2 (0.44) | L3MBTL1TP53POLB | |
| SCHEMBL22371739 | 0.81 | NPC1 (0.40) | MAPTALDH1A1KMT2AGRM5L3MBTL1 | |
| SCHEMBL1651679 | 0.79 | POLB (0.39) | MAPTALDH1A1KMT2AGRM5L3MBTL1 | |
| SCHEMBL19917122 | 0.79 | PSEN1 (0.41) | MAPTALDH1A1KMT2AGRM5L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160890-B2 | Compounds specific to adenosine A3 receptor and uses thereof | OSI PHARMACEUTICALS, INC. (US) | 2007-01-09 | — | — | US | disclosed |