Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433435 | 0.90 | RAB9A (0.50) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL14591892 | 0.89 | MAPT (0.44) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL14491714 | 0.87 | ITGB1 (0.46) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL12327918 | 0.86 | MEN1 (0.47) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL91549 | 0.83 | RAB9A (0.62) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL27578589 | 0.80 | KMT2A (0.44) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL12327268 | 0.80 | RIOK2 (0.39) | MAPTMEN1KMT2ARAB9AHDAC6 | |
| SCHEMBL14626963 | 0.78 | RAB9A (0.46) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL2432899 | 0.77 | RAB9A (0.43) | MAPTMEN1KMT2ATP53TSHR | |
| SCHEMBL2429149 | 0.77 | ITGB1 (0.55) | MAPTMEN1KMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |