Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91549 | 0.80 | RAB9A (0.62) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL2433435 | 0.78 | RAB9A (0.50) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL14626752 | 0.77 | MAPT (0.47) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL14591892 | 0.77 | MAPT (0.44) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL12327918 | 0.76 | MEN1 (0.47) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL2432847 | 0.76 | ITGB1 (0.46) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL14491714 | 0.75 | ITGB1 (0.46) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL27578589 | 0.75 | KMT2A (0.44) | RAB9AMAPTMEN1KMT2ATP53 | |
| SCHEMBL2432438 | 0.75 | NPC1 (0.48) | MAPTMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL2429653 | 0.74 | AKR1B1 (0.46) | RAB9AMAPTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |