Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 13/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 13/20 | 0.57 |
| ▸ | CFD | P00746 | 5/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592441 | 0.92 | ITGA4 (0.68) | ITGB1ITGA4CFD | |
| SCHEMBL14592439 | 0.85 | ITGA4 (0.75) | ITGB1ITGA4CFD | |
| SCHEMBL14626918 | 0.80 | ITGA4 (0.59) | ITGB1ITGA4ACKR3 | |
| SCHEMBL14626984 | 0.80 | ITGB1 (0.61) | ITGB1ITGA4 | |
| SCHEMBL14626979 | 0.79 | ITGB1 (0.63) | ITGB1ITGA4 | |
| SCHEMBL14592282 | 0.79 | ITGA4 (0.89) | ITGB1ITGA4 | |
| SCHEMBL14626775 | 0.78 | ITGB1 (0.51) | ITGB1ITGA4ACKR3 | |
| SCHEMBL14771989 | 0.76 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL14592428 | 0.75 | ITGA4 (0.67) | ITGB1ITGA4 | |
| SCHEMBL14592306 | 0.75 | ITGB1 (0.90) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |