Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 16/20 | 0.59 |
| ▸ | ITGB1 | P05556 | 15/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592436 | 0.92 | ITGA4 (0.70) | ITGA4ITGB1MAPT | |
| SCHEMBL14592437 | 0.83 | ITGA4 (0.79) | ITGA4ITGB1 | |
| SCHEMBL14771989 | 0.81 | ITGB1 (0.65) | ITGA4ITGB1KMT2A | |
| SCHEMBL14626772 | 0.80 | ITGB1 (0.57) | ITGA4ITGB1ACKR3 | |
| SCHEMBL14533967 | 0.77 | ITGB1 (0.67) | ITGA4ITGB1KMT2AMAPT | |
| SCHEMBL14626979 | 0.77 | ITGB1 (0.63) | ITGA4ITGB1 | |
| SCHEMBL14592306 | 0.77 | ITGB1 (0.90) | ITGA4ITGB1 | |
| SCHEMBL14592282 | 0.77 | ITGA4 (0.89) | ITGA4ITGB1 | |
| SCHEMBL14626984 | 0.74 | ITGB1 (0.61) | ITGA4ITGB1 | |
| SCHEMBL14592283 | 0.74 | ITGB1 (1.00) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157487-B2 | Vla-4 inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-01-02 | — | — | US | disclosed |