Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | F2 | P00734 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6661330 | 0.85 | F2 (0.52) | LMNAF2TSHRKMT2AALDH1A1 | |
| Benzoyl Peroxide SCHEMBL63 | 0.84 | LMNA (1.00) | LMNAF2TSHRTDP1KMT2A | |
| Benzoyl Peroxide SCHEMBL3467853 | 0.84 | LMNA (1.00) | LMNAF2TSHRTDP1KMT2A | |
| Benzoyl Peroxide SCHEMBL2929886 | 0.84 | LMNA (1.00) | LMNAF2TSHRTDP1KMT2A | |
| Benzoyl Peroxide SCHEMBL9407293 | 0.84 | LMNA (1.00) | LMNAF2TSHRTDP1KMT2A | |
| Benzoyl Peroxide SCHEMBL5312311 | 0.84 | LMNA (1.00) | LMNAF2TSHRTDP1KMT2A | |
| Benzyl Alcohol SCHEMBL29104386 | 0.84 | TDP1 (0.63) | LMNAF2TSHRTDP1KMT2A | |
| Methyl Benzoate SCHEMBL28229738 | 0.84 | TSHR (0.73) | LMNATSHRTDP1KMT2ASLC6A2 | |
| Benzoyl Peroxide SCHEMBL27823640 | 0.83 | LMNA (0.77) | LMNAF2TSHRTDP1KMT2A | |
| Benzyl Benzoate SCHEMBL1396786 | 0.82 | KMT2A (0.85) | LMNATSHRTDP1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494075-A2 | TEMPLATED NANOCONJUGATES | Northwestern University (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2473160-A1 | DELIVERY OF THERAPEUTIC AGENTS USING OLIGONUCLEOTIDE-MODIFIED NANOPARTICLES AS CARRIERS | Northwestern University (US) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011053940-A2 | TEMPLATED NANOCONJUGATES | NORTHWESTERN UNIVERSITY (US) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011028850-A1 | DELIVERY OF THERAPEUTIC AGENTS USING OLIGONUCLEOTIDE-MODIFIED NANOPARTICLES AS CARRIERS | NORTHWESTERN UNIVERSITY (US) | 2011-03-10 | — | — | WO | disclosed |