SCHEMBL6661330

SCHEMBL6661330

O=C(OOC(=O)c1ccc(CO)cc1)c1ccc(CO)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.52
LMNA P02545 1/20 0.52
HPGD P15428 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ADRB2 P07550 1/20 0.47
ADRB1 P08588 1/20 0.47
ADRB3 P13945 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
CYP4A11 Q02928 3/20 0.46
LOXL2 Q9Y4K0 1/20 0.45
PKM P14618 1/20 0.45
NPC1 O15118 1/20 0.45
CYP4F2 P78329 2/20 0.44
ALDH1A1 P00352 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27541699 0.86 HPGD (0.47) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL9932429 0.86 PRSS1 (0.44) F2LMNAHPGDSMN1; SMN2ADRB2
Benzoyl Peroxide SCHEMBL1462739 0.85 LMNA (0.71) F2LMNASMN1; SMN2KMT2ANPC1
SCHEMBL9932432 0.84 PRSS1 (0.42) F2LMNAHPGDSMN1; SMN2ADRB2
SCHEMBL27532336 0.82 HPGD (0.49) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL63426 0.82 LOXL2 (0.68) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL28050323 0.82 HPGD (0.45) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL28631592 0.82 LOXL2 (0.68) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL5834013 0.82 HPGD (0.45) HPGDSMN1; SMN2ADRB2ADRB1ADRB3
SCHEMBL8454935 0.82 KMT2A (0.53) LMNAHPGDSMN1; SMN2ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1220837-B1 PROCESS FOR PREPARING PEROXIDES USING MIXED ANHYDRIDES AKZO NOBEL NV (NL) 2004-08-18 EP disclosed
US-20040049070-A1 Reacting a hydroperoxide or acyl hydroperoxide with a mixed anhydride having a -C(O)-O-C(O)-O- group to form a peracid or diacyl peroxide; OVERKAMP JOHANNES WILLIBRORDUS (NL) 2004-03-11 US disclosed
US-6610880-B1 Reacting with an organohydroperoxide under basic conditions to form peracids, peresters, diacylperoxides or their hydroxy derivatives; low cost; odorless; high yield AKZO NOBEL NV (NL) 2003-08-26 US disclosed
EP-1220837-A1 PROCESS FOR PREPARING PEROXIDES USING MIXED ANHYDRIDES Akzo Nobel N.V. (NL) 2002-07-10 EP disclosed
WO-2001027078-A1 PROCESS FOR PREPARING PEROXIDES USING MIXED ANHYDRIDES AKZO NOBEL N.V. (NL) 2001-04-19 WO disclosed