Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215587 | 0.89 | NR4A2 (0.45) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL14628490 | 0.81 | HTR2A (0.40) | KDM4EALDH1A1HPGDIDO1MEN1 | |
| SCHEMBL14188730 | 0.80 | NR4A2 (0.54) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL12658120 | 0.77 | NR4A2 (0.55) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL14215611 | 0.77 | NR4A2 (0.43) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| Lynamicin A SCHEMBL12658027 | 0.76 | NR4A2 (0.61) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL14215657 | 0.74 | KDM4E (0.46) | NR4A2KDM4EALDH1A1MEN1KMT2A | |
| Lynamicin D SCHEMBL12658118 | 0.72 | NR4A2 (0.63) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL12658130 | 0.72 | NR4A2 (0.51) | NR4A2KDM4EALDH1A1HPGDPYGL | |
| SCHEMBL12658114 | 0.72 | SPR (0.42) | NR4A2KDM4EMEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |