Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215611 | 0.82 | NR4A2 (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14628181 | 0.81 | NR4A2 (0.43) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14188729 | 0.81 | KDM4E (0.46) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658122 | 0.78 | MAPT (0.49) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658120 | 0.75 | NR4A2 (0.55) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14628298 | 0.74 | MAPT (0.41) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL14215657 | 0.73 | KDM4E (0.46) | KDM4ELMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL12658219 | 0.72 | KDM4E (0.38) | HTR2AKCNH2KDM4ELMNAMEN1 | |
| SCHEMBL12658025 | 0.72 | ALPL (0.49) | MEN1KMT2AMAPTALPLHTT | |
| SCHEMBL12658199 | 0.71 | HTR2A (0.38) | HTR2AKCNH2KDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166634-B2 | Bis-indole pyrroles useful as antimicrobials agents | NEREUS PHARMACEUTICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |