Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14585344 | 0.87 | KDM1A (0.54) | KDM4EALOX15MAPK1ALDH1A1KDM1A | |
| SCHEMBL14585306 | 0.79 | KDM1A (0.54) | KDM4EALOX15MAPK1ALDH1A1KDM1A | |
| SCHEMBL14628171 | 0.78 | CACNA1G (0.45) | KDM4EALOX15MAPTNPSR1MAPK1 | |
| SCHEMBL14628155 | 0.77 | KDM1A (0.58) | KDM4EALOX15MAPK1ALDH1A1KDM1A | |
| SCHEMBL4631081 | 0.77 | KDM1A (0.63) | KDM4EALOX15MAPTNPSR1MAPK1 | |
| SCHEMBL14585338 | 0.76 | ALDH1A1 (0.57) | KDM4EALOX15MAPK1ALDH1A1KDM1A | |
| SCHEMBL14585313 | 0.76 | POLB (0.61) | KDM4EALOX15MAPTNPSR1MAPK1 | |
| SCHEMBL14585050 | 0.76 | HIF1A (0.40) | KDM4EALOX15MAPTNPSR1MAPK1 | |
| SCHEMBL14585343 | 0.75 | KDM1A (0.56) | KDM4EALOX15MAPK1ALDH1A1KDM1A | |
| SCHEMBL14585300 | 0.75 | KDM1A (0.56) | KDM4EALOX15MAPK1ALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011623-A1 | QUINAZOLINE DERIVATIVES USEFUL IN CANCER TREATMENT | SCHERING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |