Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 17/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628555 | 1.00 | PRMT5 (0.47) | PRMT5WDR77ADORA2AADKDNMT1 | |
| SCHEMBL14628570 | 0.93 | PRMT5 (0.46) | PRMT5WDR77ADORA2AADKDNMT1 | |
| SCHEMBL14609543 | 0.89 | PRMT5 (0.50) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL14628559 | 0.84 | PRMT5 (0.53) | PRMT5WDR77ADORA2AADKDNMT1 | |
| SCHEMBL30916861 | 0.83 | PRMT5 (0.45) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL3929088 | 0.83 | PRMT5 (0.45) | PRMT5WDR77ADORA2AADK | |
| SCHEMBL13301972 | 0.82 | PRMT5 (0.43) | PRMT5WDR77ADORA2AADKDNMT1 | |
| SCHEMBL13301971 | 0.81 | PRMT5 (0.41) | PRMT5WDR77ADORA2AADKDNMT1 | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12149452 | 0.81 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK | |
| Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL6422519 | 0.81 | ADORA2A (0.67) | PRMT5WDR77ADORA2AADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157434-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2007-01-02 | — | — | US | disclosed |