Beta-2'-C-Methyl-7-Deaza-Adenosine

Beta-2'-C-Methyl-7-Deaza-Adenosine

SCHEMBL6422519

CC1(O)C(O)C(CO)OC1n1ccc2c(N)ncnc21

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 4/20 0.67
▸ PRMT5 O14744 12/20 0.57
▸ WDR77 Q9BQA1 12/20 0.57
▸ ADK P55263 1/20 0.53
▸ ADORA3 P0DMS8 4/20 0.52
▸ ADA P00813 1/20 0.48
▸ ADORA2B P29275 1/20 0.48
▸ ADORA1 P30542 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14081715 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12150774 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL15093204 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL18661674 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL12149452 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628542 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL733423 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL13772636 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14628545 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3
Beta-2'-C-Methyl-7-Deaza-Adenosine SCHEMBL14640071 1.00 ADORA2A (0.67) ADORA2APRMT5WDR77ADKADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1501850-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-02-02 — — EP claimed
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 — — US claimed
WO-2003093290-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2003-11-13 — — WO claimed
WO-2007084157-A2 NUCLEOSIDE PRODRUGS FOR TREATING VIRAL INFECTIONS GENELABS TECHNOLOGIES, INC. (US) 2007-07-26 — — WO disclosed
EP-1501850-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2005-02-02 — — EP disclosed
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection GENELABS TECHNOLOGIES, INC. 2004-04-01 — — US disclosed
WO-2003093290-A2 NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION GENELABS TECHNOLOGIES, INC. (US) 2003-11-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040063658-A1 Nucleoside derivatives for treating hepatitis C virus infection HAVCR2, PNP, NTPCR ADORA2A 174/4885PRMT5 2120/4885WDR77 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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