Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14628741 | 0.89 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNAHTTTBK1 | |
| SCHEMBL14628895 | 0.89 | TBK1 (0.40) | TBK1ACKR3 | |
| SCHEMBL14091079 | 0.85 | TBK1 (0.40) | KDM4EALDH1A1LMNAHTTTBK1 | |
| SCHEMBL13390971 | 0.84 | ACKR3 (0.42) | TBK1ACKR3 | |
| SCHEMBL12533226 | 0.81 | ACKR3 (0.43) | KDM4ETBK1ACKR3 | |
| SCHEMBL12533228 | 0.80 | ACKR3 (0.42) | KDM4ETBK1ACKR3 | |
| SCHEMBL13391076 | 0.79 | ACKR3 (0.46) | KDM4EALDH1A1HTTTBK1ACKR3 | |
| SCHEMBL8225144 | 0.78 | IGF1R (0.40) | TBK1 | |
| SCHEMBL8225788 | 0.77 | GSK3B (0.47) | KDM4ETBK1 | |
| SCHEMBL12533225 | 0.77 | ACKR3 (0.48) | TBK1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010513-A1 | Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists | SCHERING CORPORATION | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010513-A1 | Carbon-linked substituted piperidines and derivatives thereof useful as histamine H3 antagonists | HRH3, HRH4, CHRM1 | KDM4E 2606/4885ALDH1A1 1129/4885LMNA 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.