Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105107 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL2369332 | 0.72 | EGLN2 (0.31) | RPS6KA5LMNA | |
| SCHEMBL29861959 | 0.71 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL30960690 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL996451 | 0.71 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL30637303 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL358864 | 0.71 | ADORA2A (0.42) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL4184827 | 0.71 | KDM4E (0.39) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL2162809 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1MAPTHPGDPPARG | |
| SCHEMBL7535290 | 0.70 | KDM4E (0.40) | KDM4EALDH1A1MAPTHPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739081-A1 | HYDRAZINO-SUBSTITUTED HETEROCYCLIC NITRILE COMPOUNDS AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |