Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463111 | 0.74 | NTRK1 (0.33) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL14629329 | 0.72 | KDM4E (0.36) | LMNARPS6KA5 | |
| SCHEMBL743402 | 0.69 | MAPK1 (0.39) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL29994236 | 0.69 | NTRK1 (0.41) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL18671569 | 0.69 | NTRK1 (0.33) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL1160659 | 0.69 | NTRK1 (0.41) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL844341 | 0.68 | HPGDS (0.41) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL24175622 | 0.65 | NTRK1 (0.34) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL18237486 | 0.65 | ADORA3 (0.37) | NTRK1LTKTYRO3NTRK2CLK4 | |
| SCHEMBL12343963 | 0.65 | ADORA2A (0.37) | NTRK1LTKTYRO3NTRK2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |