Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | APAF1 | O14727 | 3/20 | 0.50 |
| ▸ | TDP2 | O95551 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8770711 | 0.96 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL9269288 | 0.86 | ELANE (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL6230652 | 0.86 | NPC1 (0.61) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL56435 | 0.81 | ELANE (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL6029304 | 0.81 | NPC1 (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL1143212 | 0.81 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL17637911 | 0.81 | ELANE (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL3698733 | 0.77 | MCL1 (0.67) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL9175638 | 0.76 | ELANE (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL30804365 | 0.76 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020642-A1 | Structural interaction fingerprint | BIOGEN IDEC MA INC. | 2007-01-25 | — | — | US | disclosed |