Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515827 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL5515832 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL15913279 | 0.75 | ALDH1A1 (0.42) | ALDH1A1TDP1MGAMGAASI | |
| SCHEMBL2230082 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2230091 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2230088 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL120572 | 0.71 | — | — | |
| SCHEMBL27642026 | 0.70 | ALDH1A1 (0.42) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL29057321 | 0.69 | — | — | |
| SCHEMBL7068975 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161024-B2 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |