Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515827 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL5517025 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL5517022 | 0.82 | ALDH1A1 (0.33) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL1550148 | 0.80 | ALDH1A1 (0.36) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL1550149 | 0.80 | ALDH1A1 (0.36) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL1550151 | 0.80 | ALDH1A1 (0.36) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL9794476 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL14629550 | 0.78 | ALDH1A1 (0.34) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL2230082 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TET2EGLN1 | |
| SCHEMBL2230091 | 0.77 | ALDH1A1 (0.32) | ALDH1A1TET2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161024-B2 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| US-7161024-B2 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| US-7161024-B2 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| EP-1644313-A2 | PROCESS FOR THE PREPARATION AND PURIFICATION OF 2-(ALKOXYALKYLIDENE)-3-KETOALKANOIC ACID ESTERS FROM 3-KETOALKANOIC ACID ESTERS | SCHERING CORPORATION (US) | 2006-04-12 | — | — | EP | disclosed |
| US-20050027140-A1 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | SCHERING CORPORATION | 2005-02-03 | — | — | US | disclosed |
| WO-2005007608-A2 | PROCESS FOR THE PREPARATION AND PURIFICATION OF 2-(ALKOXYALKYLIDENE)-3-KETOALKANOIC ACID ESTERS FROM 3-KETOALKANOIC ACID ESTERS | SCHERING CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050027140-A1 | Process for the preparation and purification of 2-(alkoxyalkylidene)-3-ketoalkanoic acid esters from 3-ketoalkanoic acid esters | ACKR3, CCR5, CCRL2 | ALDH1A1 437/4885TDP1 3676/4885GAA 2554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.