Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13360613 | 0.83 | HPRT1 (0.36) | CYP3A4FAPCCNE1CDK2SLC29A1 | |
| SCHEMBL7263249 | 0.81 | CYP3A4 (0.49) | CYP3A4FAPHSP90AA1HSP90AB1 | |
| SCHEMBL9177023 | 0.81 | CYP3A4 (0.49) | CYP3A4FAPHSP90AA1HSP90AB1 | |
| SCHEMBL9176435 | 0.81 | CYP3A4 (0.49) | CYP3A4FAPHSP90AA1HSP90AB1 | |
| SCHEMBL14629613 | 0.81 | CYP3A4 (0.65) | CYP3A4FAPCYP2D6 | |
| SCHEMBL13360654 | 0.76 | HSP90AB1 (0.44) | CYP3A4CCNE1CDK2CYP2D6CYP1A2 | |
| SCHEMBL13328656 | 0.76 | HSP90AA1 (0.33) | CYP3A4CCNE1CDK2SLC29A1CDK1 | |
| SCHEMBL8752233 | 0.73 | HSP90AB1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL8752184 | 0.73 | HSP90AB1 (0.43) | HSP90AA1HSP90AB1 | |
| SCHEMBL13983477 | 0.72 | CYP3A4 (0.76) | CYP3A4FAPCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157448-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2007-01-02 | — | — | US | disclosed |