Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21952688 | 0.76 | KMT2A (0.42) | GAAHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL493370 | 0.73 | KMT2A (0.45) | GAAHPGDMAPTALDH1A1KMT2A | |
| SCHEMBL5542753 | 0.72 | KMT2A (0.53) | GAAHPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL432792 | 0.72 | KMT2A (0.52) | GAAHPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL494453 | 0.70 | LMNA (0.44) | GAAHPGDMAPTALDH1A1HSD17B10 | |
| SCHEMBL27341918 | 0.69 | TSHR (0.37) | GAAALDH1A1HSD17B10KMT2AABCB1 | |
| SCHEMBL1691025 | 0.68 | TSHR (0.43) | GAAMAPTHSD17B10KMT2AABCB1 | |
| SCHEMBL1823637 | 0.68 | TSHR (0.43) | GAAMAPTHSD17B10KMT2AABCB1 | |
| SCHEMBL205700 | 0.68 | TSHR (0.43) | GAAMAPTHSD17B10KMT2AABCB1 | |
| SCHEMBL15362668 | 0.68 | MAPT (0.36) | GAAHPGDMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169774-B2 | Cephalotaxane derivatives and their processes of preparation and purification | STRAGEN PHARMA S.A. (CH) | 2007-01-30 | — | — | US | disclosed |