Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SPR | P35270 | 3/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroacetic Acid SCHEMBL494452 | 0.88 | LMNA (0.44) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL11430439 | 0.85 | KMT2A (0.52) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL432793 | 0.84 | LMNA (0.45) | KMT2ALMNAMAPTTSHRSPR | |
| SCHEMBL493369 | 0.84 | KMT2A (0.45) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL494453 | 0.83 | LMNA (0.44) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL11465333 | 0.81 | KMT2A (0.49) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL5542753 | 0.81 | KMT2A (0.53) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL11465334 | 0.81 | KMT2A (0.49) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL493850 | 0.80 | MAPT (0.45) | KMT2ALMNAMAPTALDH1A1TSHR | |
| SCHEMBL493370 | 0.80 | KMT2A (0.45) | KMT2ALMNAMAPTALDH1A1SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12365663-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2025-07-22 | — | — | US | disclosed |
| US-20240287018-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | CORSAIR PHARMA INC (US) | 2024-08-29 | — | — | US | disclosed |
| US-11958822-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2024-04-16 | — | — | US | disclosed |
| US-20230331691-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | Corsair Pharma, Inc. | 2023-10-19 | — | — | US | disclosed |
| EP-4137127-A1 | PRODRUGS OF TREPROSTINIL | Corsair Pharma, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |
| US-11505535-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2022-11-22 | — | — | US | disclosed |
| EP-3712142-B1 | PRODRUGS OF TREPROSTINIL | CORSAIR PHARMA INC (US) | 2022-07-06 | — | — | EP | disclosed |
| US-11339139-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20220112173-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | Corsair Pharma, Inc. (US) | 2022-04-14 | — | — | US | disclosed |
| US-11046666-B2 | Treprostinil derivative compounds and methods of using same | Corsair Pharma, Inc. (US) | 2021-06-29 | — | — | US | disclosed |
| US-7867690-B2 | Tertiary alcohol derivative, polymer compound and photoresist composition | KURARAY CO., LTD. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| US-20090035700-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090029290-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | KURARAY CO., LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-1992650-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | Kuraray Co., Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1992651-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | Kuraray Co., Ltd. (JP) | 2008-11-19 | — | — | EP | disclosed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029290-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | ADH1A, ADH1C, ADH5 | KMT2A 1840/4885LMNA 3254/4885MAPT 412/4885 |
| US-11505535-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | KMT2A 2787/4885LMNA 1909/4885MAPT 4588/4885 |
| US-20230331691-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-12365663-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | KMT2A 2989/4885LMNA 2486/4885MAPT 4612/4885 |
| US-11958822-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-11339139-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-20090035700-A1 | TERTIARY ALCOHOL DERIVATIVE, POLYMER COMPOUND AND PHOTORESIST COMPOSITION | ADH1A, ADH1C, CCNT1 | KMT2A 950/4885LMNA 1232/4885MAPT 335/4885 |
| US-20220112173-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | KMT2A 2787/4885LMNA 1909/4885MAPT 4588/4885 |
| US-20240287018-A1 | TREPROSTINIL DERIVATIVE COMPOUNDS AND METHODS OF USING SAME | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
| US-11046666-B2 | Treprostinil derivative compounds and methods of using same | PTGIS, PTGIR, PTGER3 | KMT2A 3480/4885LMNA 774/4885MAPT 3439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.