Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635682 | 1.00 | USP30 (0.46) | USP30TACR1KDM4EPKMSTS | |
| SCHEMBL15821722 | 0.87 | PDE4B (0.57) | USP30KDM4EPKMSTSPDE4B | |
| SCHEMBL3862182 | 0.84 | NAMPT (0.53) | KDM4EPKMSTSPDE4BGPR119 | |
| SCHEMBL31706257 | 0.84 | NAMPT (0.53) | KDM4EPKMSTSPDE4BGPR119 | |
| SCHEMBL18759246 | 0.82 | GPR119 (0.55) | USP30TACR1KDM4EPKMSTS | |
| SCHEMBL14635869 | 0.82 | TACR1 (0.47) | USP30TACR1KDM4ESTSPDE4B | |
| SCHEMBL14635868 | 0.82 | TACR1 (0.47) | USP30TACR1KDM4ESTSPDE4B | |
| SCHEMBL12354139 | 0.82 | USP30 (0.55) | USP30TACR1GPR119JAK2 | |
| SCHEMBL30379998 | 0.82 | USP30 (0.46) | USP30TACR1KDM4EPKMSTS | |
| SCHEMBL26093646 | 0.82 | USP30 (0.46) | USP30TACR1KDM4EPKMSTS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |