Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14635868 | 1.00 | TACR1 (0.47) | TACR1RORCGPR119STSPDE4B | |
| SCHEMBL18759246 | 0.84 | GPR119 (0.55) | TACR1RORCGPR119STSUSP30 | |
| SCHEMBL12354139 | 0.84 | USP30 (0.55) | TACR1RORCGPR119USP30JAK2 | |
| SCHEMBL3861809 | 0.83 | NAMPT (0.52) | GPR119STSPDE4BNPC1RAB9A | |
| SCHEMBL18617599 | 0.83 | TACR1 (0.48) | TACR1RORCGPR119STSPDE4B | |
| SCHEMBL14635683 | 0.82 | USP30 (0.46) | TACR1GPR119STSPDE4BUSP30 | |
| SCHEMBL14635682 | 0.82 | USP30 (0.46) | TACR1GPR119STSPDE4BUSP30 | |
| SCHEMBL528144 | 0.79 | TACR1 (0.54) | TACR1RORCGPR119STSUSP30 | |
| SCHEMBL16272063 | 0.78 | GPR119 (0.57) | TACR1GPR119USP30KDM4EMAPT | |
| SCHEMBL19865015 | 0.78 | PDE4B (0.57) | TACR1RORCGPR119STSPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |