Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7386590 | 0.82 | GRM2 (0.45) | GRM2SLC6A2SLC6A4SLC6A3MAOB | |
| SCHEMBL1028137 | 0.80 | LMNA (0.52) | — | |
| SCHEMBL7019706 | 0.80 | LMNA (0.52) | — | |
| SCHEMBL6961092 | 0.76 | TDP1 (0.53) | GRM2 | |
| SCHEMBL13266229 | 0.72 | — | — | |
| SCHEMBL7628338 | 0.72 | GRM2 (0.53) | GRM2SLC6A2SLC6A4SLC6A3CTRB1 | |
| SCHEMBL5837795 | 0.71 | CYP2C9 (0.52) | — | |
| SCHEMBL28315131 | 0.69 | TLR9 (0.41) | GRM2TLR9MAOBCTRB1F2 | |
| SCHEMBL6661925 | 0.69 | TLR9 (0.41) | GRM2TLR9MAOBCTRB1F2 | |
| SCHEMBL6559369 | 0.69 | TSHR (0.43) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |